Quinone and hydroquinone lipids
Apexbio Technology LLC SCH900776 S-isomer 891494-64-7 20mg
SCH900776 S-isomer is a small-molecule inhibitor targeting checkpoint kinase 1 (Chk1) It is designed to inhibit Chk1 kinase activity thereby interfering with DNA damage-induced checkpoint responses and disrupting S-phase cell-cycle arrest SCH900776 S-isomer exerts its biological activity primarily through selective inhibition of Chk1 kinase (IC50 3 nM) with substantially weaker inhibition toward Chk2 (IC50 1500 nM) and CDK2 (IC50 160 nM) In cellular assays treatment with SCH900776 S-isomer mimics the genetic depletion of CHK1 by RNA interference Based on these pharmacological properties SCH900776 S-isomer holds research potential in oncology particularly in combination with DNA-damaging chemotherapeutics to study enhanced cytotoxicity and altered cell-cycle progression in tumor and leukemia cell lines
Apexbio Technology LLC Vitamin A Acetate 127-47-9 10mM (in 1mL DMSO)
Vitamin A Acetate is a small-molecule modulator involved in the regulation of cell growth differentiation and immune response It exerts its biological activity primarily through activation of retinoic acid receptors (RARs) which regulate gene transcription pathways associated with cell proliferation differentiation and immune functions In experimental studies Vitamin A Acetate influences cell morphology and growth in cultured rat glomerular epithelial cells and enhances interleukin-2 (IL-2)-producing T-cell populations in neonatal mouse lymphocytes Based on these pharmacological properties Vitamin A Acetate holds research potential in tumor inhibition immune response modulation and investigation of cell differentiation pathways
Sigma Organic Chemistry DL-?-TOCOPHEROL METHOXYPOLYETHYLENE GLYCOL SUCCINATE | 100G | 1309573-60-1
DL-?-TOCOPHEROL METHOXYPOLYETHYLENE GLYCOL SUCCINATE, 100G
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UNSPSC Code: 51171641
Storage: ROOM TEMPERATURE
Sigma Aldrich Fine Chemicals Biosciences Vitamin K2 MK 7 456788 13C1MG
Vitamin K2 also known as menaquinone is a polyisoprenoid-substitutednbspnapthoquinone. Menaquinone-7 (MK-7) is a subtype of vitamin K2. It is found in animals soy protein fermented products and is primarily produced by bacteria.Vitamin K2 (MK-7)-4AE 5 6 7 8 8AE-13C6 is a vitamin K2 isotope wherein C-4AE C-5 C-6 C-7 C-8 and C-8AE carbons are replaced by 13C6.
Sigma Aldrich Fine Chemicals Biosciences Vitamin K2 MK 4 456788 13C1MG
Vitamin K2 or menaquinone (MK) is a type of vitamin K found in animal and fermented food products. Menaquinone-4 (MK-4) is also known as menatetrenone. It is common in the human diet which is produced by bacterial conversion of vitamin K1.
Sigma Aldrich Fine Chemicals Biosciences Vitamin K1 4a56788a 13C6 91MG
Vitamin K1 also known as phylloquinone is a fat-soluble vitamin found in algae nbspcyanobacteria and plants. It is involved in the synthesis of some important proteins having applications in blood clotting and bone metabolism.Vitamin K1-4a 5 6 7 8 8a-13C6 is an isotope of vitamin K1 wherein C-4a C-5 C-6 C-7 C-8 C-8a carbons are replaced by 13C6 carbon.
Sigma Aldrich Fine Chemicals Biosciences Casein vitamin tested powd5KG
Casein is produced from skim milk. It is roughly made of 80% bovine milk protein and has only 10 to 20% essential amino acids per gram of protein.
Sigma Aldrich Fine Chemicals Biosciences MEM Vitamin Solution 100x
Synthetic/ basal media used currently contain amino acids carbohydrates vitamins and salts. Eagle minimum essential medium (MEM) is a modified version of BME (basal medium Eagle) which contains increased amounts of each amino acid. Addition of water soluble vitamins such as inositol to various culture facilitates the hatching of hamster and rabbit blastocysts. Vitamins also influence the metabolism of glucose in sheep and mouse embryos.
Sigma Aldrich Fine Chemicals Biosciences alpha Tocopherol phenyl 131MG
Tocopherol (vitamin E) is a lipid-soluble antioxidant found in whole grains nuts andnbspoils. It is known to scavenge reactive oxygen species by interacting with lipids duringnbspoxidative stress.Tocopherol-(phenyl-13C6) is an isotope of vitamin E wherein all the six phenyl carbons are replaced by 13C6 carbon.
Selleck Chemical LLC Vitamin K1 S4698-25mg
Vitamin K1 (Phyllohydroquinone Phylloquinone Phytomenadione Phytonadione) made by plants is a major type of dietary vitamin K which is well-known for its role in blood clotting Vitamin K1 is directly involved in photosynthesis
Selleck Chemical LLC Vitamin A Acetate S4083-1g
Vitamin A Acetate (Retinyl Retinol) is a group of unsaturated nutritional hydrocarbons that includes retinol retinal retinoic acid and several provitamin A carotenoids among which beta-carotene is the most important
Cayman Chemical SynthetIc VItamIn A 100mg
A cell-permeable allosteric inhibitor of Eg5 (Ki app 2 3 nM) with 10000-fold selectivity for Eg5 over a range of other mitotic kinesins
Cayman Chemical B71CD80 LNg Isoform EXrac
A building block has been used in the synthesis of LMP2 inhibitors and is a component of substance P peptide analogs
Cayman Chemical -a-Tocopherol Acetate 10g
A BET family protein inhibitor binds to BD1 in BRD2 BRD3 BRD4 and BRDT (Kds 1.6 2.1 1.7 and 5 nM respectively) as well as BD2 (Kds 5.9 6.2 6.1 and 120 nM respectively) binds to bromodomains of CBP and p300 (Kds ~100 nM for both) inhibits CpG-induced proliferation of primary CLL cells from 0.1-10 UM inhibits Ba/F3 cell-induced splenomegaly in mice from 0.5-10 mg/kg reduces tumor volume and increases survival in YUMM3.3 and D4M3.A mouse syngeneic B-RAFV600E mutant melanoma models